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Phenotype Image Detail
Image
Caption Comparison of craniofacial skeletons among E15.5 Ednratm2.1Hku/Ednratm2.1Hku (EdnralacZ/lacZ) (A), wild-type (WT) (B) and Ednratm6(Edn1)Hku/Ednra+ (EdnraEdn1/+) (C) mice. Activated Edn1/Ednra signaling (colored in pink) correlates to the formation of Meckelian cartilage (MC) and associated mandibular structures. at, ala temporalis; dnt, dentary; hy, hyoid; in, incus; ma, malleus; mx, maxilla; pl, palatine; pmx, premaxilla; *, ectopic structure.
Copyright This image is from Sato T, Proc Natl Acad Sci U S A 2008 Dec 2;105(48):18806-11. Copyright 2008 National Academy of Sciences, U.S.A. J:224515
Associated
Alleles
Symbol Name
Ednratm2.1Hku endothelin receptor type A; targeted mutation 2.1, Hiroki Kurihara
Ednratm6(Edn1)Hku endothelin receptor type A; targeted mutation 6, Hiroki Kurihara
Associated
Genotypes
Allelic Composition Genetic Background
Ednratm2.1Hku/Ednratm2.1Hku involves: 129 * C57BL/6 * ICR
Ednratm6(Edn1)Hku/Ednra+ involves: 129 * C57BL/6 * ICR
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory