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| Caption | Representative histological analyses of diseased Gt(ROSA)26Sortm2(Lmp1/CD40)Uzs/Gt(ROSA)26Sor+ Cd19tm1(cre)Cgn/Cd19+ (LMP1/CD40) and age matched control mice. (1) HE-stained normal spleen. (2) HE-stained spleen representative for diseased mutant mice, showing prominent nodular tumor infiltrates. (3) Lymphoma infiltrate within the spleen of a representative diseased mutant mouse. B cells were visualized by immunohistochemistry using an antibody specific for B220. (4) Higher magnification of section described in 3. (5) Dispersed reactive T cells within the lymphoma infiltrate were detected by an anti-CD3 specific antibody. A representative highly magnified section is shown. Bars: (1 and 2) 400 um; (3) 100 um; (4, 5, and inset) 25 um. | ||||||
| Copyright | This image is from Homig-Holzel C, J Exp Med 2008 Jun 9;205(6):1317-29, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:137122 | ||||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/09/2024 MGI 6.23 |
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