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Phenotype Image Detail
Image
Caption Phenotype of Sp2tm1.2Sus/Sp2tm1.2Sus (Sp2null) embryos. A) A Sp2null embryo at E9.5 in comparison to wild-type (Sp2wt) and heterozygous (Sp2+/-) littermates. B) An Sp2null embryo at E9.5 in direct comparison to an E8.5 Sp2wt embryo. C) Serial longitudinal sections of heterozygous Sp2 (Sp2+/-) and Sp2null embryos from day E9.0. Sp2null embryos are smaller, have not turned and have an open cranial neural tube (Nt). Ne, neural epithelium.
Copyright This image is from Baur F, PLoS One 2010;5(3):e9587, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:158671
Associated
Alleles
Symbol Name
Sp2tm1.2Sus Sp2 transcription factor; targeted mutation 1.2, Guntram Suske
Associated
Genotypes
Allelic Composition Genetic Background
Sp2tm1.2Sus/Sp2tm1.2Sus involves: 129P2/OlaHsd * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory