| Image |
|
||||
| Caption | Illustration of disease progression and variation in Pkd1tm1.1Pcha/Pkd1tm1.1Pcha (Pkd1RC/RC) mice. (A) Gross images of wild-type (WT) and homozygous mutant kidneys at 3, 6, 9 and 12 months. Macroscopic cysts become visible by 6 months. Ruler shows the SI unit cm. (B) Masson Trichrome stained kidney histology sections of homozygous mice used for physiological and histological analysis. The illustration highlights the observed disease variability among animals at the same age, and the progressive disease severity throughout aging in these outbred animals. Scale bars = 1 mm. | ||||
| Copyright | This image is from Hopp K, J Clin Invest 2012 Nov 1;122(11):4257-73 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:193544 | ||||
|
Associated Alleles |
|
||||
|
Associated Genotypes |
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/16/2024 MGI 6.23 |
|
|
|
||
Analysis Tools