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Phenotype Image Detail
Image
Caption Arrest of endochondral ossification and lack of calcification in Sp7tm1.1Rnis/Sp7tm1.1Rnis (deltaflox/deltaflox) mice. (A, B) Skeletal preparations stained with alcian blue and alizarin red at E15.5 days (A) and E18.5 days (B). WT, wild-type littermate. (C) Histology of cartilage of tibia at E16.5 days. Hematoxylin-eosin (HE) staining of WT and mutant. Lower panels show higher magnification. Scale bar: 100 um.
Copyright This image is from Nishimura R, J Biol Chem 2012 Sep 28;287(40):33179-90 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:191589
Associated
Alleles
Symbol Name
Sp7tm1.1Rnis Sp7 transcription factor 7; targeted mutation 1.1, Riko Nishimura
Associated
Genotypes
Allelic Composition Genetic Background
Sp7tm1.1Rnis/Sp7tm1.1Rnis involves: C57BL * C57BL/6NCrlj * CBA/JNCrlj * DBA

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory