| Image |
|
||||||
| Caption | Developmental defects of Ednrbs-24Pub/Ednrb+ m128-7Tpo/m128-7Tpo+ (128-7) embryos. Lateral (a and b) and frontal (c and d) views of age matched wild-type (WT) and mutant embryos at E10.5. Mutant embryos fail to complete embryonic turning; head and branchial arches are dysmorphic, and the pericardium is swollen and contains blood (b). WT embryos (c) exhibit rightward looping morphogenesis during heart development. The direction of heart looping morphogenesis is randomized in mutants. Heart looping morphogenesis is reversed in the mutant embryo (d). Embryos in (c and d) are labeled for Nkx2-5 expression to enhance visualization of the heart tube. At E10.5 the yolk sac of WT embryos (e) has formed a well-developed vasculature (arrows) compared with mutant embryos (f), which fail to form mature blood vessels in the yolk sac (arrows). | ||||||
| Copyright | This image is from Hagarman JA, Genesis 2009 Jun;47(6):392-403, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:149893 | ||||||
|
Associated Alleles |
|
||||||
|
Associated Genotypes |
|
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
||
|
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support. |
last database update 04/16/2024 MGI 6.23 |
|
|
|
||
Analysis Tools