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| Caption | Phenotype of Porcntm1Vdv/Y and Porcntm1Vdv/Porcn+ chimeric mice. (A) Hypoplastic, fused, and missing digits on right (R) and left (L) fore- (F) and hindlimbs (H) in different chimeras (C1-C4) compared to wild-type (WT). (B) Skeletal preparations of extremities shown in panel A. (C) Vertebral abnormalities in the tail of chimera 1 (C1). (D) Hydronephrosis of the right kidney and normal left kidney in C1. (E) Hypoplastic testicle in C1 and normal testicle in C5. (F) Uterine abnormalities: asymmetrical hypoplastic uterine horn in C6. (G) Gel picture showing amplification of the targeted allele in various tissues of C1. H, heart; K(L), left kidney; LU, lung; SK, skin; SP, spleen; T, testis; K(R), right kidney; LI, liver; TG, targeted allele; WT, wild-type allele. | ||||||
| Copyright | This image is from Liu W, PLoS One 2012;7(3):e32331, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:186934 | ||||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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