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Phenotype Image Detail
Image
Caption (C-K) Representative histopathology of tumors from Pik3catm1.1Waph/Pik3catm1.1Waph Ptentm1Hwu/Ptentm1Hwu (Pik3caH1047RPtendel/del) mice. Non-AdCre-exposed ovary (C), serous adenocarcinoma (D-H), and granulosa cell tumor (I-K). Staining with H&E (C-E, I, and J), p-Akt S473 (F, high-power inset), p-Rps6 (G, high power inset), pankeratin (H, adjacent uterus inset), or inhibin (K) is shown. Scale bars: bracketed, 500 mm; unbracketed, 50 mm. B, bursa; CL, corpus luteum; F, follicle; FP, fat pad.
Copyright This image is from Kinross KM, J Clin Invest 2012 Feb 1;122(2):553-7 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:184382
Associated
Alleles
Symbol Name
Pik3catm1.1Waph phosphatidylinositol 3-kinase, catalytic, alpha polypeptide; targeted mutation 1.1, Wayne A Phillips
Ptentm1Hwu phosphatase and tensin homolog; targeted mutation 1, Hong Wu
Associated
Genotypes
Allelic Composition Genetic Background
Pik3catm1.1Waph/Pik3catm1.1Waph
Ptentm1Hwu/Ptentm1Hwu
involves: 129S1/Sv * 129S4/SvJae * BALB/c * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory