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Phenotype Image Detail
Image
Caption Plcg2tm1Jni/Plcg2tm1Jni mice are protected from mBSA-induced arthritis independently of B cells. Wild-type (WT) (A, B), Plcg2tm1Jni/Plcg2tm1Jni (PLCgamma2-/-) (C, D), mice were immunized with mBSA and injected intraarticularly with mBSA to induce arthritis or with PBS as a negative control. Histological sections of control PBS or mBSA injected knees were TRAP stained. Cellular infiltrates (stars), osteoclasts (red cells) and bone erosion (arrows) are depicted. Images were taken using a Nikon inverted microscope and a CoolSnap camera, magnification 20x.
Copyright This image is from Cremasco V, PLoS One 2010;5(1):e8909, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:157619
Associated
Alleles
Symbol Name
Plcg2tm1Jni phospholipase C, gamma 2; targeted mutation 1, James N Ihle
Associated
Genotypes
Allelic Composition Genetic Background
Plcg2tm1Jni/Plcg2tm1Jni involves: 129P2/OlaHsd

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory