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Phenotype Image Detail
Image
Caption Histology of various tissues from wild-type and Npc1tm1Mbjg/Npc1tm1Mbjg mice. Tissues from 9-week-old female wild-type (WT) (A-C) and Npc1tm1Mbjg/Npc1tm1Mbjg (npc1pf/pf) (D-F) littermates were fixed, sectioned, and stained with H&E as described in Materials and Methods. Arrows (A) denote Purkinje cells that are present in cerebellum of WT mice but absent from mutant mice (Scale bars, 50 um; magnification: 40x).
Copyright This image is from Xie X, Proc Natl Acad Sci U S A 2011 Sep 13;108(37):15330-5. Copyright 2011 National Academy of Sciences, U.S.A. J:176587
Associated
Alleles
Symbol Name
Npc1tm1Mbjg Niemann-Pick type C1; targeted mutation 1, Joseph L Goldstein
Associated
Genotypes
Allelic Composition Genetic Background
Npc1tm1Mbjg/Npc1tm1Mbjg involves: 129S6/SvEvTac * C57BL/6J

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory