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Phenotype Image Detail
Image
Caption (A and B) Scanning electron microscopy analysis in P5 wild-type (wt) and Cdh23sals/Cdh23sals (salsa) mice revealed tip tenting in stereocilia of cochlear hair cells (arrowheads). (C and D) Defects in tenting in mutant mice at P60 (arrowheads in C indicater tenting in wild-type). (E-G) Tips in vestibular hair cells display normal tenting. Tip links (arrowhead in G) were preserved. (H) Quantification of tip tenting at P5 and P21. Tenting was reduced in hair cells from the medial and basal cochlear turns at P21. *, P<0.05. [Scale bars: A-D 300 nm; E and F 500 nm; G 150 nm].
Copyright This image is from Schwander M, Proc Natl Acad Sci U S A 2009 Mar 31;106(13):5252-7. Copyright 2009 National Academy of Sciences, U.S.A. J:147149
Associated
Alleles
Symbol Name
Cdh23sals cadherin 23 (otocadherin); salsa

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory