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Phenotype Image Detail
Image
Caption Histological changes in the spleen of Sirpatm1Nog/Sirpatm1Nog mice. The spleen was removed from 11-week old wild-type (+/+, left panels) or Sirpatm1Nog/Sirpatm1Nog (-/-, right panels) mice, fixed, and stained with Mayer's hematoxylin-eosin. Sections were examined with a light microscope equipped with phase-contrast optics, and megakaryocytes are indicated by arrowheads. Data are representative of three independent experiments. Original magnification: x100 (upper panels) or x400 (lower panels).
Copyright This image is from Yamao T, J Biol Chem 2002 Oct 18;277(42):39833-9 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:79592
Associated
Alleles
Symbol Name
Sirpatm1Nog signal-regulatory protein alpha; targeted mutation 1, Tetsuya Noguchi
Associated
Genotypes
Allelic Composition Genetic Background
Sirpatm1Nog/Sirpatm1Nog involves: 129P2/OlaHsd * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory