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Phenotype Image Detail
Image
Caption Agtpbp1pcd/Agtpbp1pcd mice show a moderate ataxia beginning at 3 to 4 weeks. Mutant mice are somewhat smaller than normal but may live a fairly normal life span. Males have abnormal sperm and are sterile. Females are fertile but are poor breeders. There is rapid degeneration of nearly all Purkinje cells beginning at 15 to 18 days, and a slower degeneration of the photoreceptor cells of the retina and mitral cells of the olfactory bulb.
Copyright Photo courtesy of Mouse Mutant Resource at The Jackson Laboratory. http://www.jax.org/mmr/index.html J:110244
Associated
Alleles
Symbol Name
Agtpbp1pcd ATP/GTP binding protein 1; Purkinje cell degeneration
Associated
Genotypes
Allelic Composition Genetic Background
Agtpbp1pcd/Agtpbp1pcd B6.BR-Agtpbp1pcd/J

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory