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Phenotype Image Detail
Image
Caption Histological analysis of Capn3tm1Jsb/Capn3tm1Jsb mice. Hematoxylin and eosin stained transverse muscle cryosections (7um) from mice of 129/Sv genetic background. A-D: 2 month old mice; E-L: 6 month old mice. Dystrophic changes are evident in psoas (A and E), soleus (B and F), deltoid (C and G), and tibialis anterior (D and H), whereas quadriceps (I), gastrocnemius (J), and triceps (K) present a normal aspect. Diaphragm in L presents very slight abnormalities. The main features encountered are fibers with internal nuclei (B-F, and H) or area of infiltration of mononuclear cells (A and G). A cluster of small regenerating fibers can be seen in E. Bars, 50 um.
Copyright This image is from Richard I, J Cell Biol 2000 Dec 25;151(7):1583-90, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:66862
Associated
Alleles
Symbol Name
Capn3tm1Jsb calpain 3; targeted mutation 1, Jacques S Beckmann
Associated
Genotypes
Allelic Composition Genetic Background
Capn3tm1Jsb/Capn3tm1Jsb either: 129/Sv-Capn3tm1Jsb or (involves: 129/Sv * C57BL/6)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory