About   Help   FAQ
Phenotype Image Detail
Image
Caption A and B: Photographs of 17 day old wild-type (Lmna+/+, A) and Lmnatm1Lgf/Lmnatm1Lgf (LmnaHG/HG, B) mice. The mutant mouse had a spontaneous fracture in the left forelimb (red arrow). C-F: Surface renderings of microCT scans of the skull (performed at exactly the same threshold) for a 17 day old mutant mouse (D and F) and littermate wild-type mouse (C and E). C and D: Top view of skulls. The mutant skull is misshapen, poorly mineralized, and exibits incomplete fusion of the cranial sutures (red arrow). E and F: Lateral view of skulls. The mutant skull is misshapen, with a small mandible (upper red arrow) and a short lower incisor (lower left arrow).
Copyright This image is from Yang SH, J Clin Invest 2006 Aug;116(8):2115-21 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:113119
Associated
Alleles
Symbol Name
Lmnatm1Lgf lamin A; targeted mutation 1, Loren G Fong
Associated
Genotypes
Allelic Composition Genetic Background
Lmnatm1Lgf/Lmnatm1Lgf involves: 129P2/OlaHsd * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
09/09/2014
MGI 5.19
The Jackson Laboratory