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| Caption | Phenotypes in Lmnatm1Lgf/Lmna+ mice. A; Radiograph of a 6 month old Lmnatm1Lgf/Lmna+ (LmnaHG/+) mouse and a littermate wild-type (Lmna+/+) mouse. C: Thorax of a six month old mutant mouse and a littermate wild-type mouse. Black arrowheads indicate fracture callus surrounding broken ribs. E: Surface renderings of microCT scans of the skulls of four month old mutant and and wild-type mice. Red arrows indicate a characteristic absence of the zigzag appearance of the cranial sutures and osteolytic lesions of the zygomatic arch. F: Surface renderings of microCT scans of the skulls of four month old mutant and wild-type mice. Red arrows in the mutant skull indicate micrognathia and the site of an osteolytic lesion of the zygomatic arch. H: Hematoxylin and eosin stained sections of the ascending aorta from a 7 month old mutant and littermate wild-type mouse. Original magnification, x20. | ||||
| Copyright | This image is from Yang SH, J Clin Invest 2006 Aug;116(8):2115-21 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:113119 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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