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Phenotype Image Detail
Image
Caption Nonlymphoid phenotypes in Adatm1Mw/Adatm1Mw Tg(PLADA)4118Rkmb/0 mice. Lung tissues from control (panel A) and Adatm1Mw/Adatm1Mw Tg(PLADA)4118Rkmb/0 mice (panel B) were collected at postnatal day 15, and sections were stained with hematoxylin and eosin. br, bronchiole; a, alveoli; e, bronchiolar epithelium; *, immune cells in lumen of bronchiole; large arrow, hypertrophied smooth muscle. Postnatal day 15 rib cages from control (panel C) and mutant (panel D) mice were stained with alyzarin red and azure blue to monitor bone (red) and cartilage (blue) morphology. White arrows point to costochondral junctions. * in panel D denotes severe curvature of ribs seen in mutant mice. Hematoxylin and eosin stained sections through control (panel E) and mutant (panel F) kidneys. g, glomerulus; t, convoluted tubules; * and arrows in panel F denote areas of increased blood content in mutant kidneys. Scale bar in F=100 um for A,B,E and F.
Copyright This image is from Blackburn MR, J Biol Chem 1998 Feb 27;273(9):5093-100 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:73418
Associated
Alleles
Symbol Name
Adatm1Mw adenosine deaminase; targeted mutation 1, Maki Wakamiya
Tg(PLADA)4118Rkmb transgene insertion 4118, Michael R Blackburn
Associated
Genotypes
Allelic Composition Genetic Background
Adatm1Mw/Adatm1Mw
Tg(PLADA)4118Rkmb/0
involves: 129S7/SvEvBrd * C57BL/6

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory