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| Caption | Skeletal phenotype of Bpnt2Gt(RST634)Byg/Bpnt2Gt(RST634)Byg mutant mice. A: E18.5 Bpnt2Gt(RST634)Byg/Bpnt2Gt(RST634)Byg (gt/gt, Right) mice exhibit shortened limbs compared with wild-type (WT, Left) littermates. B-E: Whole-mount preparations of wild-type and mutant E18.5 embryonic skeletons stained with Alcian blue (AB) and Alizarin red (AR). C: Isolated forelimbs of stained embryos depicting shortened scapula (s), humerus (h), radius (r), and ulna (u) in mutant mice compared with wild-type. D: Increased magnification of stained rib cages, ventral view. Note reduced spacing between ribs and length of sternum (st) in mutant mice. E: Dorsal view of wild-type and mutant AB/AR stained skulls demonstrating similar shape and size of parietal (p) and frontal (fr) bones between genotypes (outlined in black). Scale bars: 2 mm. | ||||
| Copyright | This image is from Frederick JP, Proc Natl Acad Sci U S A 2008 Aug 19;105(33):11605-12. Copyright 2008 National Academy of Sciences, U.S.A. J:139706 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/09/2024 MGI 6.23 |
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