About   Help   FAQ
Phenotype Image Detail
Image
Caption Morphological abnormalities of membrane system in Jph1tm1Hta/Jph1tm1Hta skeletal muscle. Longitudinal ultrathin sections of hindlimb (A-D) and jaw (E-H) muscles were analyzed using electron microscopy. Muscle preparations were derived from wild-type (A-E) and Jph1tm1Hta/Jph1tm1Hta (C and G) neonates immediately after birth, and wild-type (B and F) and mutant (D and H) neonates around 15 hours after birth. In mutant muscles, morphology of the sarcoplasmic reticulum (SR) worsened after birth, although mitochondria and myofibril retained normal structures. Scale bar, 1.0um.
Copyright This image is from Ito K, J Cell Biol 2001 Sep 3;154(5):1059-67, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:77652
Associated
Alleles
Symbol Name
Jph1tm1Hta junctophilin 1; targeted mutation 1, Hiroshi Takeshima
Associated
Genotypes
Allelic Composition Genetic Background
Jph1tm1Hta/Jph1tm1Hta involves: 129S4/SvJae * C57BL/6J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
04/16/2024
MGI 6.23
The Jackson Laboratory