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Phenotype Image Detail
Image
Caption A: Gated cardiac magnetic resonance imaging (MRI). Representative short axis (transverse) images at the mid-level of wild-type (WT) and Cav3tm1Mls/Cav3tm1Mls (Cav-3 KO) mice during diastole. Arrows point to the left ventricle. Note that the left ventricle wall thickness is increased significantly in mutant mice. LV, left ventricle. B: Graphic representation. A bar graph of the left ventricular wall thickness of mutant hearts at 2 and 4 months of age is shown and compared with age-matched wild-type control mice. Note the progressive increases in mutant left ventricle wall thickness from 2 to 4 months (n=5 for each group tested, p <0.05).
Copyright This image is from Woodman SE, J Biol Chem 2002 Oct 11;277(41):38988-97 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:79453
Associated
Alleles
Symbol Name
Cav3tm1Mls caveolin 3; targeted mutation 1, Michael P Lisanti
Associated
Genotypes
Allelic Composition Genetic Background
Cav3tm1Mls/Cav3tm1Mls involves: 129/Sv * C57BL/6J * SJL

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory