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Phenotype Image Detail
Image
Caption A: Dorsal view of 10 day old wild-type and Krt6a/Krt6btm1Cou/Krt6a/Krt6btm1Cou mice. Note the size difference between the littermates. B: Wild-type tongue. The surface is smooth and uniform. C: Tongue from mutant mouse. White plaques cover the dorsal surface, extending from the posterior region (right) near the pharynx towards, but not reaching, the tip of the tongue (left). D: Paws from wild-type mice are similar to mutant mice. E: The paw of the mutant mouse appears smaller, probably due to poor nutrition and slow growth. Development of fur and nails do not appear altered in mutant mice.
Copyright This image is from Wong P, J Cell Biol 2000 Aug 21;150(4):921-8, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:64033
Associated
Alleles
Symbol Name
Krt6a/Krt6btm1Cou keratin 6B; targeted mutation 1, Pierre A Coulombe
Krt6a/Krt6btm1Cou keratin 6A; targeted mutation 1, Pierre A Coulombe
Associated
Genotypes
Allelic Composition Genetic Background
Krt6a/Krt6btm1Cou/Krt6a/Krt6btm1Cou involves: 129S2/SvPas * C57BL/6 * DBA/2
Krt6a/Krt6btm1Cou/Krt6a/Krt6btm1Cou involves: 129S2/SvPas * C57BL/6 * DBA/2

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/16/2014
MGI 5.20
The Jackson Laboratory