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Phenotype Image Detail
Image
Caption Hematoxylin and eosin stained sections of gastric epithelium of 9 week old wild type (+/+, A) and Slc9a4tm1Ges/Slc9a4tm1Ges (-/-, B and C) mice. As compared with wild type, the glandular stomach of mutant mice was characterized by reduction in the number of readily discernable parietal and chief cells and an increase in the number of mucous and relatively undifferentiated cells. When observed under increased magnification, compared with wild type glandular stomach (D), the mutant stomach (E) exhibited decreased cell size and an increase in interglandular connective tissue (arrows). Scale bar, 50um.
Copyright This image is from Gawenis LR, J Biol Chem 2005 Apr 1;280(13):12781-9 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:98566
Associated
Alleles
Symbol Name
Slc9a4tm1Ges solute carrier family 9 (sodium/hydrogen exchanger), member 4; targeted mutation 1, Gary E Shull
Associated
Genotypes
Allelic Composition Genetic Background
Slc9a4tm1Ges/Slc9a4tm1Ges involves: 129S6/SvEvTac * Black Swiss

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory