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Phenotype Image Detail
Image
Caption Examination of wild type and Mmp20tm1Jdb/Mmp20tm1Jdb mouse molars. Scanning electron micrograph of a first maxillary molar from a wild type (A) and Mmp20tm1Jdb/Mmp20tm1Jdb mouse (B). Dashed lines encircle the enamel-free areas present on each molar. Note the pattern of enamel-free areas that are typical of rodent molars at the marsal plateau of the cusps (A). In contrast, the first molar from the mutant mouse contains very little enamel (B). The only enamel that remains is the enamel that surrounds the crown near the gingival margin. Most of the enamel has delaminated from the dentin.
Copyright This image is from Caterina JJ, J Biol Chem 2002 Dec 20;277(51):49598-604 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:80925
Associated
Alleles
Symbol Name
Mmp20tm1Jdb matrix metallopeptidase 20 (enamelysin); targeted mutation 1, John D Bartlett
Associated
Genotypes
Allelic Composition Genetic Background
Mmp20tm1Jdb/Mmp20tm1Jdb involves: 129P2/OlaHsd * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory