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Phenotype Image Detail
Caption A: Time course of TUNEL staining in lumbar dorsal root ganglias (DRGs) of wild type or Ndntm1.1Mus/Ndn+ (Ndn KO) mice. Shown are the box-plots describing the number of TUNEL positive cells for lumbar DRGs; statistical comparisons were made using the Mann-Whitney test; asterisks show differences that are statistically significant (*, p<0.05). B: Double immunoflourescence labelling for TUNEL (in red) and Neurofilament (in green) in a lumbar ganglion of an E12.5 mutant embryo. In this figure, one immunopositive-cell for Neurofilament in the field whose nuclei are labelled by the apoptosis detection method (arrow). C: Double-labelling for TUNEL (in red) and BrdU (in green) after 2 hr injection; co-labelling was never observed, indicating that precursors are not dying in the Ndntm1.1Mus/Ndn+ mice. Scale bar: 10um (B and C).
Copyright This image is from Andrieu D, BMC Dev Biol 2006;6():56, an open-access article, licensee BioMed Central Ltd. J:119656
Symbol Name
Ndntm1.1Mus necdin; targeted mutation 1.1, Francoise Muscatelli
Allelic Composition Genetic Background
Ndntm1.1Mus/Ndn+ B6.129S2-Ndntm1.1Mus

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