About   Help   FAQ
Phenotype Image Detail
Image
Caption Tumor located in the stomach of a Mbd4tm1Wed/Mbd4tm1Wed Apctm1Rak/Apc+ mouse with characteristic features of microadenoma, composed of a cluster of neoplastic glands of varying sizes and shapes. The tumor cells in the glands are crowded and show enlarged nuclei and hyperchromatic staining. Hematoxylin/eosin x200.
Copyright This image is from Wong E, Proc Natl Acad Sci U S A 2002 Nov 12;99(23):14937-42. Copyright 2002 National Academy of Sciences, U.S.A. J:80319
Associated
Alleles
Symbol Name
Apctm1Rak APC, WNT signaling pathway regulator; targeted mutation 1, Raju Kucherlapati
Mbd4tm1Wed methyl-CpG binding domain protein 4; targeted mutation 1, Winfried Edelmann
Associated
Genotypes
Allelic Composition Genetic Background
Apctm1Rak/Apc+
Mbd4tm1Wed/Mbd4tm1Wed 		involves: 129/Sv * 129P2/OlaHsd * C57BL/6 * SJL
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory