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Phenotype Image Detail
Image
Caption GpnmbR150X/GpnmbR150X irides at (F) 4 months, (G) 9 months and (H) 20 months. From 1-5 months, mutant mouse eyes were indistinguishable from wild type eyes. Near 6 months, mutant mouse eyes developed a pronounced peripupillary swelling accompanied by a pronounced accumulation of clump cells on the iris surface. These swellings remained prominent to the oldest ages examined. The iris surface maintained an overall normal morphology during the first year, after which time it became increasingly atrophic, and accumulations of dispersed pigment were visible on the lens and cornea.
Copyright This image is from Anderson MG, BMC Biol 2006;4():20, an open-access article, licensee BioMed Central Ltd. J:128215
Associated
Alleles
Symbol Name
GpnmbR150X glycoprotein (transmembrane) nmb; iris pigment dispersion
Associated
Genotypes
Allelic Composition Genetic Background
GpnmbR150X/GpnmbR150X B6.D2-GpnmbR150X

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory