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Phenotype Image Detail
Image
Caption A: Hematoxylin and eosin staining of a normal E10.5 placental labyrinth showing trophoblasts and nucleated erythrocytes in the embryonic vessels and non-nucleated maternal erythrocytes. B: Hematoxylin and eosin staining of a Vhltm1Wml/Vhltm1Wml E10.5 placental labyrinth lacking embryonal vasculogenesis. Note the presence of embryonic vessels with nucleated erythrocytes on the edge of the thin labyrinth that have not invaded the labyrinth (arrows). C: Hematoxylin and eosin staining of E11.5 mutant mouse placental showing hemorrhage into the abnormal labyrinth. Magnification: A & B: x300; C: x150
Copyright This image is from Gnarra JR, Proc Natl Acad Sci U S A 1997 Aug 19;94(17):9102-7. Copyright 1997 National Academy of Sciences, U.S.A. J:42486
Associated
Alleles
Symbol Name
Vhltm1Wml von Hippel-Lindau tumor suppressor; targeted mutation 1, W Marston Linehan
Associated
Genotypes
Allelic Composition Genetic Background
Vhltm1Wml/Vhltm1Wml involves: 129S1/Sv * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory