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Phenotype Image Detail
Caption A: Hematoxylin and eosin staining of a normal E10.5 placental labyrinth showing trophoblasts and nucleated erythrocytes in the embryonic vessels and non-nucleated maternal erythrocytes. B: Hematoxylin and eosin staining of a Vhltm1Wml/Vhltm1Wml E10.5 placental labyrinth lacking embryonal vasculogenesis. Note the presence of embryonic vessels with nucleated erythrocytes on the edge of the thin labyrinth that have not invaded the labyrinth (arrows). C: Hematoxylin and eosin staining of E11.5 mutant mouse placental showing hemorrhage into the abnormal labyrinth. Magnification: A & B: x300; C: x150
Copyright This image is from Gnarra JR, Proc Natl Acad Sci U S A 1997 Aug 19;94(17):9102-7. Copyright 1997 National Academy of Sciences, U.S.A. J:42486
Symbol Name
Vhltm1Wml von Hippel-Lindau tumor suppressor; targeted mutation 1, W Marston Linehan
Allelic Composition Genetic Background
Vhltm1Wml/Vhltm1Wml involves: 129S4/SvJae * C57BL/6

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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