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Phenotype Image Detail
Image
Caption Cross sections of the cochlea from the temporal bones of (A) wild type and (B) EdnrbWS4/EdnrbWS4 mice. Note the thin stria vascularis (SV) and shift of Reissner membrane (RM) toward the stria vascularis in the homozygous mutant mouse. Severity of endolymphatic collapse was variable in each cochlea; in this particular cochlea, endolymphatic space was partially collapsed. While outer hair cells (OHC) are visible in the organ of Corti on basement membrane (BM) in the wild type mouse, the organ of Corti is severely degenerated in the homozygous mouse and hair cells are not discernible. Scale bars: 100um
Copyright This image is from Matsushima Y, Mamm Genome 2002 Jan;13(1):30-5 and is displayed with the permission of Springer Science + Business Media, Inc., New York who owns the copyright. J:76584
Associated
Alleles
Symbol Name
EdnrbWS4 endothelin receptor type B; Waardenburg syndrome 4
Associated
Genotypes
Allelic Composition Genetic Background
EdnrbWS4/EdnrbWS4 involves: BALB/c * MSM

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/18/2014
MGI 5.20
The Jackson Laboratory