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Phenotype Image Detail
Image
Caption Skeletal comparison between wild type and Itgb2tm2Bay/Itgb2tm2Bay mice. A: Faxitron analysis demonstrates a decreased bone density in the femurs of 5 week old Itgb2tm2Bay/Itgb2tm2Bay mice (right) as compared with their wild type counterparts (left). C: Hematoxylin and eosin staining on the metaphysis area of the femurs shows diminished trabecular bone structure in the homozygous mutant mice (right) as compared with wild type mice (left). D: Representative images of the distal femur metaphysis on microcomputed tomography analysis revealed decreased bone volume, trabecular bone number, trabecular bone thickness, and an increased trabecular bone space. E: Alizarin red and Alcian blue double skeletal staining for bone (red) and cartilage (blue) of 1 week old homozygous mutant mice (right) and wild type littermates (left)>
Copyright This image is from Miura Y, Proc Natl Acad Sci U S A 2005 Sep 27;102(39):14022-7. Copyright 2005 National Academy of Sciences, U.S.A. J:101407
Associated
Alleles
Symbol Name
Itgb2tm2Bay integrin beta 2; targeted mutation 2, Baylor College of Medicine
Associated
Genotypes
Allelic Composition Genetic Background
Itgb2tm2Bay/Itgb2tm2Bay B6.129S7-Itgb2tm2Bay

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/08/2014
MGI 5.17
The Jackson Laboratory