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Phenotype Image Detail
Image
Caption Paravalbumin immunohistochemistry of midsagittal cerebellar sections from 5 month old wild type (Upper) and Atmtm1Fwa/Atmtm1Fwa (Lower) mice reveals the altered dendritic arborization of Purkinje cells in homozygous mice. C: This can also be observed in Bodian-stained sections from 1 year old mice, wild type (Upper) and homozygous mutant mice (Lower). D: Lucifer-yellow-injected wild type (+/+) and homozygous (y/y)mmutant Purkinje cells dislaying either the prototypic morphology (+/+) or premature dendritic branching (y/y), which can result in multiple dendrites emanating from the soma (Upper y/y cell).
Copyright This image is from Borghesani PR, Proc Natl Acad Sci U S A 2000 Mar 28;97(7):3336-41. Copyright 2000 National Academy of Sciences, U.S.A. J:61201
Associated
Alleles
Symbol Name
Atmtm1Fwa ataxia telangiectasia mutated; targeted mutation 1, Frederick W Alt
Associated
Genotypes
Allelic Composition Genetic Background
Atmtm1Fwa/Atmtm1Fwa involves: 129S4/SvJae * C57BL/6

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory