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Phenotype Image Detail
Caption A: Transverse and longitudinal profiles of the connecting cilia (CC). Rpgrip1tm1Tili/Rpgrip1tm1Tili and wild type mouse CC appear similar in the microtubule arrays, transmembrane assemblings, and ciliary necklaces. B: Longitudinal sections through wild type mouse photoreceptor, illustrating the normal morphology of the apical inner segment, CC and outer segment. C: In the homozygous mutant, disk diameters are greatly expanded and orientation is altered. Enlarged disks appear bending upward (left) or downward (right). D: A lower-magnification image of the mutant mouse retina showing several photoreceptors. Abbreviations: OS: outer segment; IS: inner segment. Scale bars: 0.2um
Copyright This image is from Zhao Y, Proc Natl Acad Sci U S A 2003 Apr 1;100(7):3965-70. Copyright 2003 National Academy of Sciences, U.S.A. J:82755
Symbol Name
Rpgrip1tm1Tili retinitis pigmentosa GTPase regulator interacting protein 1; targeted mutation 1, Tiansen Li
Allelic Composition Genetic Background
Rpgrip1tm1Tili/Rpgrip1tm1Tili involves: 129S4/SvJae * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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MGI 6.14
The Jackson Laboratory