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Phenotype Image Detail
Image
Caption Cardiac abnormalities in Grk2tm1Mca/Grk2tm1Mca mouse embryos visualized with hematoxylin and eosin stained sections of whole embryos. Two sections each are shown at the aortic valve and left atrioventricular canal level. A & C are of the wild type embryo. B & D are of the homozygous mutant embryo. Structures are labeled as follows: B, bronchi; DA, descending aorta; EC, endocardial cushion; IVF, interventricular foramen; IVS, interventricular septum; JRDA, junction of the right dorsal aorta; LA, left atrium; LAVC, left atrioventricular canal; LV, left ventricle; RA, right atrium; RV, right ventricle; T, trachea.
Copyright This image is from Jaber M, Proc Natl Acad Sci U S A 1996 Nov 12;93(23):12974-9. Copyright 1996 National Academy of Sciences, U.S.A. J:36567
Associated
Alleles
Symbol Name
Grk2tm1Mca G protein-coupled receptor kinase 2; targeted mutation 1, Marc Caron
Associated
Genotypes
Allelic Composition Genetic Background
Grk2tm1Mca/Grk2tm1Mca involves: 129

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory