About   Help   FAQ
Phenotype Image Detail
Caption A: Wild-type tubules show continuous peripheral layer of meiocytes with SCP3 staining. B: Nearly 50% of fourth generation Terctm1Rdp/Terctm1Rdp (G4) tubules exhibit complete absence of or very few meiocytes with SCP3 staining. Green, SCP3 elements; blue, nuclear chromosomes stained with DAPI. C: Rare apoptosis of wild-type seminferous tubules. D: Extensive apoptosis, indicated by green or yellow in the Terctm1Rdp/Terctm1Rdp seminferous tubules. Red, nuclear staining with propidium iodide.
Copyright This image is from Liu L, Proc Natl Acad Sci U S A 2004 Apr 27;101(17):6496-501. Copyright 2004 National Academy of Sciences, U.S.A. J:89751
Symbol Name
Terctm1Rdp telomerase RNA component; targeted mutation 1, Ronald DePinho
Allelic Composition Genetic Background
Terctm1Rdp/Terctm1Rdp involves: 129/Sv * C57BL/6J * SJL

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.15
The Jackson Laboratory