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| Caption | (A) 5 week old Fgfr3tm2Wei/Fgfr3+ (right) with littermate +/+ control (left) the Fgfr3tm2Wei/Fgfr3+ is easily distinguished by dwarfism, as well as a rounded head. (B) Growth curve of the Fgfr3tm2Wei/Fgfr3+ right) and wild-type littermate. (C) Showing the distortion of the brain in the Fgfr3tm2Wei/Fgfr3+ mouse. (D) Skeletal defects in the Fgfr3tm2Wei/Fgfr3+ (upper), arrow points to the craniocervical junction and thoracic kyphosis; arrowhead indicates the facial shortening and overgrowth of incisor teeth. (E-H) Skull comparison of the Fgfr3tm2Wei/Fgfr3+ (G & H) and the wild-type (E&F) mice. Dorsal view E & G. Ventral view F & H. Abbreviations: foramen magnun (fm); frontal bone (fr); incisor teeth (inc); interparietal bone (ip); mandible (md); nasal bone (na); occipital bone (occ); parietal bone (pa); zygomatic arch (zg); mutant dwarf mouse (Mut); wild-type (Wt) | ||||
| Copyright | This image is from Wang Y, Proc Natl Acad Sci U S A 1999 Apr 13;96(8):4455-60. Copyright 1999 National Academy of Sciences, U.S.A. J:54829 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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