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Molecular Image Detail
Image
Caption Generation of the Ightm3Mnz allele. (A) Schematic representation of the gene targeting strategy. The targeting vector is shown. LoxP sites are indicated as red triangles, I-SceI sites are indicated as blue circles, and frt sites are indicated as black bars. Diphtheria toxin A (DTA) was used for negative selection. The I-SceI site is underlined. The LoxP site was present in the hygromycin targeting backbone.
Copyright This image is from Bothmer A, J Exp Med 2010 Apr 12;207(4):855-65, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:159173
Associated
Alleles
Symbol Name
Ightm3Mnz immunoglobulin heavy chain complex; targeted mutation 3, Michel C Nussenzweig

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory