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Image
Caption Generation of the Cttntm1.1Dvst and Cttntm1.2Dvst alleles. (A) Domain organization of the cortactin protein and gene targeting strategy showing the partial genomic organization of the Cttn locus in WT, targeted, loxP flanked (floxed Cttntm1.1Dvst), and deleted (Cttntm1.2Dvst) alleles. The vector carrying a neomycin resistance cassette to target the wild-type cortactin allele by homologous recombination in murine ES cells is depicted. Targeted ES cells were injected into blastocysts.
Copyright This image is from Schnoor M, J Exp Med 2011 Aug 1;208(8):1721-35, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:177602
Associated
Alleles
Symbol Name
Cttntm1.1Dvst cortactin; targeted mutation 1.1, Dietmar Vestweber
Cttntm1.2Dvst cortactin; targeted mutation 1.2, Dietmar Vestweber

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory