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| Caption | A) Diagram illustrating the gene-targeting strategy used to produce the Cryabtm1.1Ady knock-in mice. The numbered rectangles represent exons and the starred exon 3 indicates the mutated exon. Restriction sites relevant to Southern blot analysis are shown together with the size of the restriction fragments. Lox P sites are represented as closed triangles. The 3' probe that was used for Southern blot analysis is shown below the mutated allele. Neor represents the neomycin cassette, which was excised by homologous recombination after introduction of the knock-in plasmid and the Turbo-Cre plasmid. Bold arrows indicate the PCR primers (pcr1 and pcr2) used to detect the wild-type (WT) and mutated alleles. | ||||
| Copyright | This image is from Andley UP, PLoS One 2011;6(3):e17671, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:171679 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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