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Caption (A) Targeting strategy. The diagram shows the wild-type locus, the targeting construct (BAC), and the targeted locus before (WNK1iloxneo allele) and after (WNK1ilox allele) FLP recombination which generates the Wnk1tm2.1Juha allele. Cre-mediated recombination can be used to produce the WNK1-FHHt allele. The black triangles represent the loxP sites, and the yellow and orange trapezoids correspond to the wild-type and mutated (FRT3) FRT sites, respectively.
Copyright This image is from Vidal-Petiot E, Proc Natl Acad Sci U S A 2013 Aug 27;110(35):14366-71. Copyright 2013 National Academy of Sciences, U.S.A. J:200742
Associated
Alleles
Symbol Name
Wnk1tm2.1Juha WNK lysine deficient protein kinase 1; targeted mutation 2.1, Juliette Hadchouel
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/09/2024
MGI 6.23 		The Jackson Laboratory