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Molecular Image Detail
Caption Generation of the Smyd2tm1.1Fben allele. (A) The targeting vector contains a short (0.6 kb) and a long (7.4 kb) arm of homology, a neomycin resistance cassette (neo) for positive selection, and a thymidine kinase cassette for negative selection. Two site-specific recombination sites were employed in vivo. Flp recombinase was used to delete the neo marker from the mouse germline and Cre recombinase afterwards allows for the conditional deletion of Smyd2 in selected tissues. Two loxP sites flank the region to be deleted. This region includes exon 1 of Smyd2.
Copyright This image is from Diehl F, PLoS One 2010;5(3):e9748, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:158898
Symbol Name
Nkx2-5tm2(cre)Rph NK2 homeobox 5; targeted mutation 2, Richard P Harvey
Smyd2tm1.1Fben SET and MYND domain containing 2; targeted mutation 1.1, Felix B Engel

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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