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Molecular Image Detail
Image
Caption Generation of Braftm2Urr (BRafnfl), Braftm2.1Urr (BRaffl), and Braftm2.2Urr (BRafdel) alleles. In the conditional Braf allele, Braftm2Urr, exon 3 encoding part of the Ras-binding domain is flanked by loxP sites (arrowheads). Deletion of the neomycin resistance gene in the Brafnfl mice generated the Braftm2.1Urr (BRaffl) allele. Deletion of both exon 3 and the neomycin resistance gene generated the Braftm2.2Urr (BRrafdel) allele. Positions of primers used in PCR reactions to distinguish the different alleles are shown.
Copyright This image is from Pfeiffer V, PLoS One 2013;8(3):e58259, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:199842
Associated
Alleles
Symbol Name
Braftm2.1Urr Braf transforming gene; targeted mutation 2.1, Urr R Rapp
Braftm2.2Urr Braf transforming gene; targeted mutation 2.2, Urr R Rapp
Braftm2Urr Braf transforming gene; targeted mutation 2, Urr R Rapp

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory