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Molecular Image Detail
Image
Caption (A) Targeting strategy to generate the Il7rtm1.1Asin (IL-7Rfl) allele. Numbered boxes = exons, gray boxes = out of frame exons as a result of Cre-mediated deletion. NeoR = neomycin resistance cassette. Black triangles = loxP sites. Gray ovals = frt sites. H, V = HindIII and EcoRV restriction sites, respectively. Location of 5' and 3' probes for Southern blot is indicated. Cre-mediated recombination can be used to conditionally delete exon 3 (IL-7Rdelta) of Il7r.
Copyright This image is from McCaughtry TM, J Exp Med 2012 Nov 19;209(12):2263-76, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:190889
Associated
Alleles
Symbol Name
Il7rtm1.1Asin interleukin 7 receptor; targeted mutation 1.1, Alfred Singer

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
01/18/2022
MGI 6.17
The Jackson Laboratory