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| Caption | Targeted disruption of the mouse Muc16 gene. (A) Strategy used for Muc16 gene targeting to generate the Muc16tm1Bhr allele. Organization of the mouse Muc16 gene, structure of the targeted allele, targeting vector, location of Southern probes, protein region recognized by anti-mouse MUC16 polyclonal antibody, and primers for RT-PCR (6F, 10R; 22F, 27R; 38F, 43R). Bc, BclI; Bg, BglI; BgII, BglII; RI, EcoRI; RV, EcoRV; Sc, ScaI; Ss, SspF, lacZ, IRES-lacZ-pA; NEO, PgkneobpA; triangle, loxP sites. | ||||
| Copyright | This image is from Cheon DJ, PLoS ONE 2009;4(3):e4675, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:147379 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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