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| Caption | A, a schematic representation of the Smad2 conditional targeting strategy. The upper panel shows a partial genomic map of the wild-type gene used in the creation of the target vector. PGK-neo-poly(A) cassette flanked by loxP sites were introduced downstream of exon 8. An additional loxP site was introduced upstream of exon 7, generating the Smad2tm1.1Nomu allele (Smad2flox allele). Arrows indicate selection of the homologous recombinants and Cre-mediated deletion of exons 7 and 8. | ||||
| Copyright | This image is from Wang L, J Biol Chem 2011 May 27;286(21):18766-74 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:173787 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/09/2024 MGI 6.23 |
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