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Molecular Image Detail
Image
Caption (A) Schematic diagram of Scn4a showing the locations of the hypokalemic periodic paralysis (HypoPP) mutations at arginines in S4 voltage sensor domains (red triangles). The targeting construct (22.4 kb) for homologous recombination in mouse Scn4a to generate the Scn4atm1.1Cann allele is shown below.
Copyright This image is from Wu F, J Clin Invest 2011 Oct 3;121(10):4082-94 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:178228
Associated
Alleles
Symbol Name
Scn4atm1.1Cann sodium channel, voltage-gated, type IV, alpha; targeted mutation 1.1, Stephen C Cannon

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory