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| Caption | Insulinoma formation in Tg(Ins2-Akt1*)3Mbb/0 (MyrAkt1) mice. Sections of pancreas stained with H&E or immunostained with insulin. Representative images of islets (I), adenomas (A), multilobular adenomas (MA), carcinoma, and lung metastasis are shown. Scale bar: 250 um. (D) Islet hypertrophy, dysplasia, hyperplasia, and malignant transformation in mutant mice. Representative sections of pancreata immunostained with the HA antibody to visualize MyrAkt1 expression and counterstained with hematoxylin. Scale bar: 50 um. | ||||
| Copyright | This image is from Alliouachene S, J Clin Invest 2008 Nov;118(11):3629-38 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:144599 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/09/2024 MGI 6.23 |
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