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Phenotype Image Detail
Image
Caption Pdcd6iptm1.2Adz/Pdcd6iptm1.2Adz (KO) epithelia display apoptotic cell extrusion. (a) 3D confocal reconstruction of wild-type (WT) and mutant whole-mount choroid plexus (CP) showing tunnel+ and Myosin IIa+ cells being extruded from epithelial cell layer of mutant CP (n = 3). (b) Scanning electron microscopy (SEM) images of cluster of cells extruded from mutant tracheal epithelial cells. Scale bar, 5 um.
Copyright This image is from Campos Y, Nat Commun 2016 Jun 23;7():11876, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:238436
Associated
Alleles
Symbol Name
Pdcd6iptm1.2Adz programmed cell death 6 interacting protein; targeted mutation 1.2, Alessandra d'Azzo
Associated
Genotypes
Allelic Composition Genetic Background
Pdcd6iptm1.2Adz/Pdcd6iptm1.2Adz either: (involves: 129S1/Sv) or (involves: 129S1/Sv * C57BL/6)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory