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Caption Morphological changes in the prefrontal cortex of Hbegftm1Hhar/Hbegftm1Hhar Tg(Six3-cre)69Frty/0 (KO) mice. (a) Representative photomicrographs showing morphology of pyramidal neuronsin cortical layer III of the prefrontal cortex from control (left) and mutant (right) mice. Scale bar = 20 um. (b) Representative photomicrographs of apicaldendritic segments from control (left) and mutant (right) mice. Scale bar = 8 um. (c) High-magnification images of apical dendritic segments from adult control (left) and mutant (right) mice. In pyramidal neurons, spine density is reduced, although dendritic length is normal. Scale bar = 2 um.
Copyright This image is from Oyagi A, PLoS One 2009;4(10):e7461, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:154094
Symbol Name
Hbegftm1Hhar heparin-binding EGF-like growth factor; targeted mutation 1, Hideaki Hara
Tg(Six3-cre)69Frty transgene insertion 69, Yasuhide Furuta
Allelic Composition Genetic Background
involves: C57BL/6 * CBA * DBA/2

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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