Phenotype Image Detail

Image

Caption

Fluorescent images of E9.5-10.5 DAPI stained (a) wild-type and (b) Aldh1a2^grim/Aldh1a2^grim (grimace) embryos. Abbreviations: ba, branchial arch; lnp, lateral nasal process; md, mandibular process; mnp, medial nasal process, ma, maxillary process; np, nasal placode; op, optic vesicle; ov, otic vesicle. Arrowheads highlight agenesis, hyopoplasia and abnormal patterning and development of the pharyngeal arches in mutant embryos compared to wild-type.

Copyright

This image is from Sandell LL, Genesis 2011 Apr;49(4):342-59, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright. J:171522

Associated Alleles

Symbol	Name
Aldh1a2^grim	aldehyde dehydrogenase family 1, subfamily A2; grimace

Associated Genotypes

Allelic Composition	Genetic Background
Aldh1a2^grim/Aldh1a2^grim	involves: 129S1/Sv * C57BL/6 * FVB/NJ