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Phenotype Image Detail
Image
Caption Diaminobenzidine (DAB)-enhanced Perls' iron staining of hippocampus and cerebellum of aged Ireb2tm1.1Eal/Ireb2tm1.1Eal (Irp2-/-) and wild-type (WT) mice. Coronal sections of hippocampus (A) (slide 41) and cerebellum (B) (slide 58) used for quantification of iron in CA1 pyramidal neurons. Dotted boxes indicate the WT (6B-4) and the mutant (6A-3) mice used for DAB-enhanced Perls' staining in File S1 and File S2. Ages of male mice: WT, 65-71 weeks; mutant (Irp2-/-), 46-53 weeks.
Copyright This image is from Zumbrennen-Bullough KB, PLoS One 2014;9(6):e98072, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:217335
Associated
Alleles
Symbol Name
Ireb2tm1.1Eal iron responsive element binding protein 2; targeted mutation 1.1, Elizabeth A Leibold
Associated
Genotypes
Allelic Composition Genetic Background
Ireb2tm1.1Eal/Ireb2tm1.1Eal B6J.129-Ireb2tm1.1Eal

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory