Phenotype Image Detail

Image

Caption

(A) Histological sections of epididymis from wild-type (Lamin C2+/+) and Lmna^tm1Rben/Lmna^tm1Rben (Lamin C2-/-) mice showing the complete absence of mature sperm in the mutant. Scale bar 100 um. (B) In situ labelling of apoptotic cells in testis sections from wild-type and mutant animals using the TUNEL revealed significantly increased cell death in the mutant mice. Scale bar 50 um.

Copyright

This image is from Link J, PLoS Genet 2013;9(1):e1003261, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:223056

Associated Alleles

Symbol	Name
Lmna^tm1Rben	lamin A; targeted mutation 1, Ricardo Benavente

Associated Genotypes

Allelic Composition	Genetic Background
Lmna^tm1Rben/Lmna^tm1Rben	involves: 129S1/Sv * 129X1/SvJ